dosage_ode

dosage_ode, a Python code which uses a system of ordinary differential equations (ODE) to simulate the blood levels of a medicinal drug that should stay between medicinal and toxic limits.

The drug level can be modeled by a set of first-order linear differential equations. If we define:

  A = medicine_in_intestines,
  B = plasma_level.  

  dA/dt = - absorption_rate * A + intake
  dB/dt = - excretion_rate  * B + absorption_rate * A

Licensing:

The computer code and data files described and made available on this web page are distributed under the MIT license

Languages:

dosage_ode is available in a MATLAB version and an Octave version and a Python version.

Related Data and Programs:

python_ode, Python codes which sets up various systems of ordinary differential equations (ODE).

Reference:

1. Soraya Dhillon, Andrzej Kostrzewski,
   Clinical Pharmacokinetics,
   Pharamceutical Press, 2006
   ISBN: 978-0-85369-571-4.

Source Code:

• dosage_ode.py, the source code.
• dosage_ode.sh, runs the test.
• dosage_ode.txt, the output file.

• dosage_ode_levels.txt, the drug concentration over time.
• dosage_ode.png, a plot of the drug level over time.